特殊文章 – 抗性高血压管理:2020年更新

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所属分类:疗效
摘要

抗性高血压(RH)由于心血管疾病和卒中而不是高血压诱导较高的发病率和死亡率,而无需治疗抗蚀剂……

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特殊文章 - 抗性高血压管理:2020年更新

摘要

抗高血压(RH)诱导较高的发病率和死亡率因心血管疾病而且卒中比高血压无需治疗。新的准则将RH定义为血压(BP)≥130/ 80mmHg,患者≥3种不同类别或BP的抗高血压剂<130/80 mmHg in a patient taking ≥4 antihypertensive drugs. According to the new definition, pseudo-resistance due to error in BP measurement, white coat effect and medication nonadherence must be excluded to make the diagnosis of RH. This 2020 update focuses on the lifestyle and antihypertensive drug management of RH and includes recent proof-of-principle trials of renal nerve ablation in hypertension. Stepwise evidence-based pharmacologic treatment of RH includes optimization of the 3-drug regimen, substitution of a thiazide-like for a thiazide diuretic and addition of a mineralocorticoid receptor antagonist as the fourth drug. Non-evidence-based recommendations include addition of a β-blocker as the fifth drug and switching to a minoxidil-based regimen as the final step in achieving BP control.

关键词

抗性高压治疗术术

缩写血压监测综合学院生心学致毒素转换酶抑制作用达达阿米米森氏菌属Arbangiotensin受体骨盆:肾素比率抗性治疗耐药性高压术群体Bloctureccbalcium通道Blockerckdchronic Banks Blockerckdchronic andlanddiseaseCPAPcontinuous气道正压通气pressureCVDcardiovascular diseaseDASHDietary途径停止HypertensionDENERHTNThe肾脏去神经支配的HypertensioneGFRestimated肾小球滤过rateHBPMhome血压monitoringLAlong-actingMRAmineralocorticoid受体antagonistNSAIDSnon甾体类抗炎drugsPATHWAY-2Prevention和高血压的治疗算法为基础的治疗,2RHresistant hypertensionSBPsystolic血液pressureSIMPLICITY HTN-3SIMPLICITY™Hypertension- 3,患者患者患者患者的3倍耐力Medsymplicity Spyral™多电极肾脏除去系统标准医疗治疗的标准医疗治疗耐药性高血压,使用Lifestyle Modification促进HealthView全文

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